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Bayesian Approaches to Clinical Trials and Health-Care Evaluation (Statistics in Practice)

by David J. Spiegelhalter, Keith R. Abrams, Jonathan P. Myles

Publisher: John Wiley & Sons
Publication Date: Monday, January 26, 2004
Number of Pages: 406
ISBN: 0471499757


Book Summary:
READ ALL ABOUT IT!

David Spiegelhalter has recently joined the ranks of Isaac Newton, Charles Darwin and Stephen Hawking by becoming a fellow of the Royal Society. Originating from the Medical Research Council’s biostatistics unit, David has played a leading role in the Bristol heart surgery and Harold Shipman inquiries.  

Order a copy of this author’s comprehensive text TODAY! 

The Bayesian approach involves synthesising data and judgement in order to reach conclusions about unknown quantities and make predictions. Bayesian methods have become increasingly popular in recent years, notably in medical research, and although there are a number of books on Bayesian analysis, few cover clinical trials and biostatistical applications in any detail. Bayesian Approaches to Clinical Trials and Health-Care Evaluation provides a valuable overview of this rapidly evolving field, including basic Bayesian ideas, prior distributions, clinical trials, observational studies, evidence synthesis and cost-effectiveness analysis.
Covers a broad array of essential topics, building from the basics to more advanced techniques.

  • Illustrated throughout by detailed case studies and worked examples
  • Includes exercises in all chapters
  • Accessible to anyone with a basic knowledge of statistics
  • Authors are at the forefront of research into Bayesian methods in medical research
  • Accompanied by a Web site featuring data sets and worked examples using Excel and WinBUGS - the most widely used Bayesian modelling package


Bayesian Approaches to Clinical Trials and Health-Care Evaluation is suitable for students and researchers in medical statistics, statisticians in the pharmaceutical industry, and anyone involved in conducting clinical trials and assessment of health-care technology.

The Bayesian approach involves collecting data from past experience in order to reach conclusions about future events. Bayesian methods have become increasingly popular in recent years, notably in medical research. There are a large number of books on Bayesian analysis, but very few that cover clinical trials and biostatistical applications in any capacity. There is no book available that is introductory in nature and covers such a broad array of essential topics. This book provides a valuable overview of this rapidly evolving field, not only for statisticians in the pharmaceutical industry, but also to anyone involved in conducting clinical trials and HTA work. Comprehensive coverage of Bayesian methods in medical research

  • Illustrated throughout by case studies and worked examples
  • Authors are at the forefront of research into Bayesian methods in medical research
  • Suitable for those with a limited statistical background
  • Accompanied by a Web site featuring data sets and worked examples in WinBUGS - the most widely accepted Bayesian modelling package



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Last Updated: 24 November 2007.