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Advances in Cancer Research, Volume 74 (Advances in Cancer Research) by George F. Vande Woude, George Klein Publisher: Academic Press Publication Date: Wednesday, April 15, 1998 Number of Pages: 223 ISBN: 0120066742

Book Summary: This volume of Advances in Cancer Research begins with a review by M. Roussel of the key effectors of cytokine and growth factor signaling to the cell cycle block. P 53 and how it controls the cell cycle, genomic stability, and apoptosis are reviewed by M.R.A. Mowat. The third chapter, by T.S. Lewis and colleagues, discusses the effect of MAP kinase cascades as examples of signal transduction mechanisms in signaling pathways. In Chapter 4, Sozi et al. Review the frequent abnormalities found in the FHIT gene in a variety of cancer-derived cell lines. Volume 74 concludes with an overview by J.J. Hsuan and co-workers of the cellular functions of PtdlnsP2 and the regulation of its biosynthesis.

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