Book Summary:
Following it's discovery in E.coli by Kundig, Ghosh and Rosema thirty seven years ago, a wealth of information has accumulated on the bacterial Phosphotransferase system (PTS). Since then the PTS has been found in a wide variety of different bacteria where it has been recognised to play a pivotal role in numerious aspects of bacterial cellular physiology. While the primary functions of this system involve sugar reception, transport and phosphorylation, the secondary functions include the regulation, both directly and indirectly, of important metabolic pathways. In this book, Internationally recognised authors review the current research on the PTS, discuss the multifaceted structural and functional aspects of the system and attempt to provide a realistic forecast of future discoveries. Study of this important system will contribute to our understanding of prokaryotic physiology and pathogenesis, will allow major advances in biotechnology, and will result in the development of agents capable of effectively combating harmful microorganisms. |