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Genomics Books
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61 - 70 of 1000 Most Recent Genomics Books, Journals and Periodicals Page 7 of 100 Pages

Genomic implications of oxidative stress in Caco-2 cellsGenomic implications of oxidative stress in Caco-2 cells
by Theresa Herring
Publisher: ProQuest / UMI
Publication Date: Monday, March 20, 2006
Description: To study the effects of oxidative stress on the intestinal tract, Caco-2 cells were treated with a 75 micromolar hydrogen peroxide (H 2O2) solution for 30 minutes. After RNA isolation and purification, analysis of gene expression was obtained via microarrays. Gene expression levels were confirmed by RT-PCR. Results indicate no...more

Yureiboya comparative genomicsYureiboya comparative genomics
by David Scott Johnson
Publisher: ProQuest / UMI
Publication Date: Monday, March 20, 2006
Description: We use the ascidians, Ciona savignyi and Ciona intestinalis, as model systems to investigate current issues in comparative genomics. First, we develop genomics resources for Ciona savignyi , including a genome sequencing effort. We then characterize the relationship between noncoding sequence constraint and function. We find that the high level...more

Model-based clustering of genomic aberrations: Generalizing the instability selection network modelModel-based clustering of genomic aberrations: Generalizing the instability selection network model
by Hyuna Yang
Publisher: ProQuest / UMI
Publication Date: Monday, March 20, 2006
Description: This research develops two model-based clustering methodologies for characterizing marginal properties and dependence structure in cancer genomic aberrations recorded by comparative genomic hybridization (CGH), one of the techniques used to measure changes in DNA copy number in tumor cells. The first model is the instability selection tree-like network model (ISTN)...more

Genomics tools for elucidating the function of trait conferring genesGenomics tools for elucidating the function of trait conferring genes
by Michael David Lynch
Publisher: ProQuest / UMI
Publication Date: Monday, March 20, 2006
Description: We have developed a variety of functional genomics tools for the identification and characterization of trait conferring genes in bacteria. These include: a series of broad host range vectors for the creation and screening of large a representational genomic libraries, a system for transposon based insertional mutagenesis that can provide...more

Alu retrotransposition-mediated genomic variation within the primate orderAlu retrotransposition-mediated genomic variation within the primate order
by Pauline Ann Callinan
Publisher: ProQuest / UMI
Publication Date: Sunday, March 19, 2006
Description: Retrotransposons are an active family of mobile elements within primate genomes and the Short INterspersed Element (SINE) Alu is the most abundant member. These non-autonomous elements are responsible for introducing genomic diversity on an intra- and inter species level that is useful in studies of forensic identity, population genetics, and...more

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Genomic analysis of host pathogen interactions between Fusarium graminearum and its graminaceous hostsGenomic analysis of host pathogen interactions between Fusarium graminearum and its graminaceous hosts
by Rubella Sanyal Goswami
Publisher: ProQuest / UMI
Publication Date: Sunday, March 19, 2006
Description: Fusarium head blight or scab, a destructive disease of small grains is caused by members of the Fusarium graminearum species complex, which is comprised of at least nine distinct species. They produce trichothecene mycotoxins, including deoxynivalenol along with its acetylated derivatives and nivalenol. Thirty-one different strains, representing eight species of...more

Mobile elements and primate genomic variationMobile elements and primate genomic variation
by Jinchuan Xing
Publisher: ProQuest / UMI
Publication Date: Sunday, March 19, 2006
Description: Mobile elements comprise approximately 50% of the human genome and have significant influence on human genomic architecture and stability. SINEs (Short INterspersed Elements) are a class of non-autonomous mobile elements that are usually <500 bp in length and have no open reading frames. As the most successful SINEs in primate,...more

Genomics analysis of large-scale biological networks and their relationshipsGenomics analysis of large-scale biological networks and their relationships
by Haiyuan Yu
Publisher: ProQuest / UMI
Publication Date: Sunday, March 19, 2006
Description: Biological networks are of great current interest in biology, particularly with the publication of a number of large-scale networks in yeast. Among them, four (expression, interaction, regulatory, and metabolic) networks have special importance, because they describe four processes that are almost sufficient for a cell to manage its basic activities....more

Functional genomics in mouse embryonic stem cellsFunctional genomics in mouse embryonic stem cells
by Moshe Pritsker
Publisher: ProQuest / UMI
Publication Date: Sunday, March 19, 2006
Description: Embryonic stem (ES) cells have unique capacities of self-renewal and differentiation into other cell types. ES cells are widely used for studies of development processes and thought to provide a system for design of novel transplantation therapies. Perspective biomedical and research applications require an understanding of mechanisms that maintain the...more

Computational studies on evolution and functionality of genomic repeatsComputational studies on evolution and functionality of genomic repeats
by Can Alkan
Publisher: ProQuest / UMI
Publication Date: Sunday, March 19, 2006
Description: Human DNA consists of a large number of repeat sequences. The repeat sequences can be in the form of tandem repeats and interspersed repeats and cover more than 60% of the human genome sequence. Segmental repeats are a result of duplication events that have occurred during the evolution of human...more

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