 | Data mining techniques for SELDI MS proteomic data -- Dissertation
by Asha Serah, Thomas
Publisher: ProQuest / UMI
Publication Date: Monday, August 21, 2006
Description: The goal of this study was to review and explore artificial intelligence strategies on proteomic data from mass spectrometry. Serum samples collected from congestive heart failure patients and controls are analyzed in this study using linear and non linear decision models. The models had similar performance and low correlation and...more
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 | Derivatization strategies as an aid to assist separation and mass spectral properties of peptides in proteomics -- Dissertation
by Samir, Julka
Publisher: ProQuest / UMI
Publication Date: Friday, August 18, 2006
Description: In the past few years, derivatization based strategies have dominated the wide spread effort of differential chemical analysis of biological systems, especially in the field of proteomics. Derivatization strategies have been used to quantify changes in protein expression, to simplify complex protein mixtures and to enhance representation of low abundance...more
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 | Structural and proteomic analyses of the gammaherpesviruses KSHV and RRV -- Dissertation
by Christine Marie, O\\\'Connor
Publisher: ProQuest / UMI
Publication Date: Thursday, August 17, 2006
Description: Rhesus monkey rhadinovirus (RRV) is one of the closest phylogenetic relatives to the human pathogen, Kaposi\'s sarcoma-associated herpesvirus (KSHV)---a gammaherpesvirus and the etiologic agent of three malignancies associated with immunosuppression. Unlike KSHV, RRV displays robust lytic phase growth and replicates to high titer and, thus, holds promise as an effective...more
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 | Bayesian Inference for Gene Expression and Proteomics
by Marina Vannucci
Publisher: Cambridge University Press
Publication Date: Monday, July 24, 2006
Description: The interdisciplinary nature of bioinformatics presents a challenge in integrating concepts, methods, software, and multi-platform data. Although there have been rapid developments in new technology and an inundation of statistical methodology and software for the analysis of microarray gene expression arrays, there exist few rigorous statistical methods for addressing other...more
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 | Proteomics for Biological Discovery
by Timothy D. Veenstra, John R. Yates
Publisher: Wiley-Liss
Publication Date: Friday, June 23, 2006
Description: Written by recognized experts in the study of proteins, Proteomics for Biological Discovery begins by discussing the emergence of proteomics from genome sequencing projects and a summary of potential answers to be gained from proteome-level research. The tools of proteomics, from conventional to novel techniques, are then dealt with in...more
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 | Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases (Wiley - Interscience Series on Mass Spectrometry)
by Dominic M. Desiderio, Nico M. Nibbering
Publisher: Wiley-Interscience
Publication Date: Monday, June 12, 2006
Description: Methodology and applications of redox proteomics The relatively new and rapidly changing field of redox proteomics has the potential to revolutionize how we diagnose disease, assess risks, determine prognoses, and target therapeutic strategies for people with inflammatory and aging-associated...more
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 | Antibody-based proteomic analysis of the subtilisin multi-gene family in Arabidopsis thaliana
by Ming Li
Publisher: ProQuest / UMI
Publication Date: Thursday, March 23, 2006
Description: Arabidopsis thaliana has 54 subtilisin-related protease (subtilase) genes, but what role these proteases play in the plant is largely unknown. Fifty-four gene-specific primer pairs were designed and applied to RT-PCR studies on aboveground tissues of 7-day etiolated seedlings and seedlings grown in a 16-h photoperiod. Thirty-one subtilases were found to...more
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 | Proteomic profiling following cryopreservation
by Martin Joseph Vogel
Publisher: ProQuest / UMI
Publication Date: Wednesday, March 22, 2006
Description: To provide a better understanding of the biomolecular response of cells following cryopreservation, Bcl-XL and Bax levels were analyzed by western blot and changes in the proteomic profile were followed via surface enhanced laser desorption ionization-time of flight (SELDI-TOF) technology. In this study, human dermal fibroblast cells were cryopreserved in...more
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 | Extraction and selection of relevant information in proteomic mass spectra for biomarker identification
by Grzegorz M. Boratyn
Publisher: ProQuest / UMI
Publication Date: Monday, March 20, 2006
Description: A diagnostic decision of a physician in often based on measurements of some quantities in body tissue or fluids. Those measurements serve as markers of specific diseases and their stages. Biomedical research is constantly seeking for markers to diagnose diseases earlier and with better precision. Proteins have been recently regarded...more
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 | Solution isoelectric focusing and its application in comparative proteomic studies of nuclear proteins
by Yanming An
Publisher: ProQuest / UMI
Publication Date: Monday, March 20, 2006
Description: In proteomic research, experimental and computational approaches are combined to provide global analysis of the entire proteomes of cells and tissues. The identification and quantification of multiple proteins, which constitute a specific biological system, are important for understanding complex problems in biology. The coupling of highly efficient separations and mass...more
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