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Healthcare IT and Biotechnology News Release
Date of Publication: Monday, July 25, 2011

Biotie Advances Clinical Program for SYN120 with Imaging Study at Johns Hopkins Center of Excellence

Biotie Advances Clinical Program for SYN120 with Imaging Study at Johns Hopkins Center of Excellence
Biotie today announced the start of a Phase 1 clinical study using positron emission tomography (PET) imaging to investigate brain concentrations of SYN120, a potential treatment for cognitive disorders including Alzheimer's disease and schizophrenia.

The trial of healthy volunteers is being conducted by Dr Dean Wong at the Johns Hopkins University School of Medicine in the United States to determine occupancy of the 5-HT6 receptor in the brain following different doses of SYN120. This will help to establish the appropriate dose for subsequent Phase 2 trials.

"This is an important step in our development program for SYN120, which we believe is a potential best-in-class compound targeting the 5HT6 receptor with significant potential to help patients suffering from Alzheimer's disease and other diseases affecting cognition," commented Dr Stephen Bandak, Biotie's Chief Medical Officer. "We are particularly pleased to collaborate with the leading PET center for this type of research in the United States."

Results from the study are expected in the first half of 2012.

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    Last Updated: 24 November 2007.